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Limitation of use: Though there are various danger components for preterm birth, security and efficacy of Makena continues to be shown only in Females with a previous spontaneous singleton preterm birth. It's not intended for use in Girls with various gestations or other possibility components for preterm start.
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In the multicenter, randomized, double-blind, automobile (placebo)-managed clinical trial, the protection and efficiency of Makena for that reduction of the potential risk of spontaneous preterm delivery was analyzed in women having a singleton pregnancy (age 16 to forty three several years) who experienced a documented history of singleton spontaneous preterm birth (defined as shipping at below 37 weeks of gestation next spontaneous preterm labor or premature rupture of membranes).
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Hydroxyprogesterone caproate is actually a synthetic progestin. The system by which hydroxyprogesterone caproate cuts down the risk of recurrent preterm start is just not acknowledged.
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